Prevention and post-exposure management of occupational exposure to Ebola virus

MA Moso; CK Lim; E Williams; C Marshall; J McCarthy; DA Williamson

Journal article

Prevention and post-exposure management of occupational exposure to Ebola virus

MA Moso, CK Lim, E Williams, C Marshall, J McCarthy, DA Williamson

Lancet Infectious Diseases | Published : 2024

DOI: 10.1016/S1473-3099(23)00376-6

Abstract

There have been significant advances in the prevention and management of Ebola virus disease (EVD) caused by Zaire Ebola virus (ZEBOV), including the development of two effective vaccines, rVSV-ZEBOV and Ad26.ZEBOV/MVA-BN-Filo. In addition, ZEBOV monoclonal antibodies have become first-line therapy for EVD. However, the 2022–23 outbreak of Sudan Ebola virus (SUDV) in Uganda has highlighted the gap in current therapies and vaccines, whose efficacy is uncertain against non-ZEBOV species. Health-care and laboratory staff working in EVD treatment centres or Ebola virus diagnostic and research laboratories face unique risks relating to potential occupational exposure to Ebola viruses. Given the s..

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University of Melbourne Researchers

Chuan Lim Author

Caroline Marshall Author

James McCarthy Author

Deborah Williamson Author

Related Projects (1)

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Antimicrobial resistance (AMR) is a huge threat to public health, both in Australia and globally. In some instances, having an AMR infection..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

MAM is supported by a National Health and Medical Research Council (NHMRC) Postgraduate Scholarship and an Australian Government Research Training Program Scholarship. DAW is supported by an NHMRC Investigator Grant (APP1174555) .